As the demand for sustainable fuels and chemicals increases, biological production from renewable feedstocks has become a means of supplementing or replacing petroleum-based products. Leveraging its EDGE® metabolic and strain engineering technology, OPXBIO has designed and built microbial strains and bioprocesses for the production of fatty acids, 3-hydroxypropionic acid (3-HP), and other industrial biochemicals using a variety of existing and emerging feedstocks. OPXBIO’s proprietary methods for producing malonyl-CoA, the key intermediate for fatty acid and 3-HP production pathways, allows for the development of micro-organisms capable of achieving production rates, titers, and yields that enable the large scale bioproduction of unique and drop-in products at costs competitive with petroleum- and plant-based sources. Fermentation-derived fatty acids and their derivatives represent attractive options for supplying growing markets in synthetic lubricants, polymer chemistry, agroculture and other fields. 3-HP is a recognized platform biochemical with several valuable market applications. One such market, te monomer acrylic acid, represents an $8 Billion global opportunity with end-product applications in paints and coatings, textiles, water treatment, and superabsorbent polymers.  OPXBIO’s progress in developing the malonyl-CoA platform for bio-based chemical and fuel production will be highlighted, along with commercialization plans.

Biobased chemical and fuel development at OPXBIO

249th National Meeting (2015)

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