Cell cytosol, cell organelles, serum and interstitial fluids all may be considered complex, concentrated chemical systems. The colloidal properties of complex, concentrated mixtures may result in preferential solvation of macromolecules by other macromolecules. Charge-charge interactions between molecules provide the longest-range interaction. However, what governs the charge on biomolecules, particularly proteins, is still being examined. This talk will focus on the molecular features that contribute to their proximity energy, and how these features may lead to order in a complex system.

Proximity energies and their consequences in living systems

249th National Meeting (2015)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.