Cysteine and glutathione are involved in many biological processes. Both the reduced and the oxidized forms of the two molecules are present in biological systems. Among a number of analytical techniques used to determine these molecules, electroanalytical technique has demonstrated the advantages of simplicity, fast analysis time, and low cost. In this research, cyclic voltammetry is used to study the electroreactivity of the reduced and oxidized forms of the molecules at various kinds of screen-printed electrodes including carbon, gold, and modified electrodes. The peak potentials and currents are studied in relation to the experimental parameters of potential ranges, scan rates, and supporting electrolytes. Pulse voltammetry is used to quantify the molecules. The effects of electrode materials and experimental parameters on the electrochemistry of the molecules are discussed. The quantitative determinations for the reduced and oxidized forms of the molecules are compared.

Voltammetric determination of sulfur-containing biomolecules using screen-printed electrodes

249th National Meeting (2015)

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