Sugar-metal ion interactions are not only ubiquitous in biological processes but are also vital in functions such as signal transduction, intercellular recognition and targets of bacterial or viral infections in cells. In an attempt to understand these interactions, water soluble synthetic models with carboxylic rich ligand, N-[2-carboxybenzomethyl]-N-[carboxymethyl]-β-alanine (H3camb), with Zn2+and Cu2+ metal ions have been synthesize and fully characterize using several spectroscopic and crystallographic techniques. The complexes are found to be very active in interacting with biologically important sugars such as D-Glucose, D-Xylose, D-Mannose and a polyalcohol enzyme inhibitor (Xylitol) in aqueous alkaline conditions. The synthesis, characterization and interaction of the complexes with the substrates, determination of binding constants and specific mode of binding will be discussed.

Investigation of sugar-Cu(II) and Zn(II) complexes' interactions in aqueous alkaline media

249th National Meeting (2015)

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