249th National Meeting (2015)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.

American Chemical Society

New Reactions and Methodology

Chemo-enzymatic synthesis of key intermediates (S)-γ-hydroxymethyl-α,β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone via lipase-mediated Baeyer-Villiger oxidation of levoglucosenone

A K2CO3 mediated regioselective synthesis of indole/pyrrole-fused 1,4-oxazines: An unexpected indole-fused azlactone synthesis

HOF-CH3CN Probably the best oxygen transfer agent organic chemistry has to offer

Near-IR uncaging chemistry: discovery, and applications

Rh(III)-catalyzed C-H activation of N-enoxyphthalimides

Butyrolactone synthesis via polar radical crossover cycloaddition reactions: Diastereoselective synthesis of methylenolactocin and protolichesterinic acid

Dramatic kinetic isotope effects (kie), solvent effects, and tunneling in directed ortho metallation (DOM)

Flow chemistry for sustainable chemical manufacturing

Synthesis of functionalized benzenoid macrocycles: Templates for carbon nanotube synthesis

Synthesis of bridged bicycles via additional steps of metal carbene cascade reaction

Automated simultaneous catalyst screening and cross-coupling reaction optimization in a continuous-flow microreactor system

Efficient synthesis of N-alkylated amides from nitriles and alcohols catalyzed by the combination of gold and iridium complexes

Regioselective synthesis of chloro/bromostyrenes: Chloro/bromotrimethylsilane-nitrate salt as efficient reagent system

Mechanistic studies and applications of tertiary amine trapping of HDDA-generated benzynes

Synthesis of highly functionalized aryl sulfides from HDDA-generated benzynes: Scope and mechanisms

Photochemistry of o-nitroarenes: Trifluoromethylated o-nitrobenzyl sytems as efficient photosynthons for selective trifluoromethylated arenes and heteroarenes

Pentadehydro-Diels-Alder (PDDA) reaction.Part 1: Cycloisomerization of triynes to a,3-dehydrotoluene derivatives and their trapping reactions

Enantioselective cycloadditions of aminoazaxylylenes photogenerated via proton transfer in aromatic imines and oxazolines offer expedited access to diverse polyheterocyclic moleculararchitectures

Unusual rearrangement of 3-acyl-2-alkoxyfurans enabling appendage of a carbon substituent at C-2: Application to the synthesis of furanolabdanes

Site-selective aliphatic C-H halogenation using N-haloamides

Photoredox catalysis in a complex pharmaceutical setting

Protodecarboxylation of unstablized carboxylic acids and malonic acid derivatives through photoredox catalysis

C-H activation and C-C bond formation through cross-coupling reaction by using potassium organotrifluoroborates

Chiral anti-diols from alpha-oxyaldehydes

Multicomponent reactions in deep eutectic solvents

Metal-free methodology for the preparation of sterically hindered ynones and its application to the synthesis of natural products

Efficient assembly of epoxyisoindoline derivatives through a tandem Diels-Alder Ugi-Smiles process

Synthesis of 5, 6, 7, and 8-membered oxacycles by silver and gold catalysis

Rh(III)-catalyzed C(sp3)H allylic functionalization of N-tosylamides :An unexpected formation of azabicyclic compounds

Intramolecular [3 + 2] cyclocondensations of alkenes with indolidenes and indolidenium cations

Development of complexity generating and stereoselective carbon carbon bond forming reactions

Accessing triplet nitrenes by visible light triplet sensitization of azides

Copper (I) catalyzed synthesis of enaminones from thioamides and α-diazocarbonyl compounds

New applications of dimethylsulfoxide as a terminal oxidant

Cerium-free Luche reduction in the presence of alumina

Regioselective C-H activation of azine N-oxides in arylation and dimerization

Tetrabutylammonium bromide: Catalytic abilities in C-O activation

Catalytic olefin hydroamination with aminium radical cations: A photoredox method for direct C-N bond formation

Iron catalyzed α-C-H oxidation of tertiary amines mimicking cytochrome P450 activity

Synthetic clays as new catalysts for aerobic oxidation

Progress toward the development of catalysts for the intermolecular bromoetherification and bromoesterification of electron rich alkenes

Palladium-catalyzed decarboxylative C–C bond formation of secondary benzyl electrophiles

One-pot tandem cyclization of alkynes to generate polycyclic products

Epoxide approach towards the synthesis of the polypropionate acid moiety of dolabriferol

Stereoselective homoallylation with cyclopropanated allylation reagents

From carbon to cancer: The impact of reaction development on natural products and designed materials synthesis

Highly active multidentate molybdenum (VI) catalysts for alkyne metathesis

2,2,2-Trichloroethyl aryldiazoacetates as robust reagents for site-selective C–H functionalization

Rh(III)-catalyzed synthesis of 2,3-dihydropyridines initiated by C-H activation

Transition metal catalyzed reactions for the functionalization of cubane and triptycene scaffolds

Enantioselective N-heterocyclic carbene-catalyzed β-hydroxylation of enals using nitroarenes: An atom transfer reaction that proceeds via single electron transfer

Amidoalkylation of unactivated olefins enabled by proton-coupled electron transfer

Metal- and reagent-free highly selective anodic cross-coupling reaction

Surprising organic synthesis: Serendipitous discovery of a novel cascade process

Catalyst development for enantioselective atom transfer C-H functionalization reactions

N Boc amines to oxazolidinones via Pd(II)/Bis-sulfoxide/Brønsted acid co-catalyzed allylic C−H oxidation

Triphenylphosphine promoted hydroalkoxylation of divinyl sulfone: An ol-ene “Click” reaction?

Development of Corey-Seebach umpolung reagents in palladium-catalyzed cross-coupling reactions

Synthesis of N-phthalimido-O-acyl-N,O-acetals from aldehydes and their conversion into α-branched phthalimides

Pentadehydro-Diels-Alder (PDDA) reaction Part 2: Cycloadditions of allenynes with nitriles to give pyridine derivatives

Rhodium (I) catalyzed carbon-carbon bond activation: Decarbonylation of ynones

New synthetic approaches to biologically active amino containing natural Ppoducts: Total synthesis of oxybenzophenanthridines

Transition metal catalyzed redox-triggered C-C couplings of alcohols via transfer hydrogenation

Synthesis of 6-hydroxyquinoline starting from glycerol via improved microwave-assisted modified Skraup reaction and Bamberger rearrangement

Radical decarboxylation in micellar media for the formulation of new surfactants

Microwave-assisted dehydration of polyols in aqueous media

Examining the scope of ISES hits: Pd-catalyzed halo- and pseudohalometalation/carbocyclization transformations

New dehydrative glycosylation with phosphonium anhydrides

New Reactions and Methodology

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<br /> Chemo-enzymatic synthesis of key intermediates (<i>S</i>)-γ-hydroxymethyl-α,β-butenolide and (<i>S</i>)-γ-hydroxymethyl-γ-butyrolactone <i>via </i>lipase-mediated Baeyer-Villiger oxidation of levoglucosenone