<br/>Silver nanomaterials are being increasingly used as a surface coating in medical devices to inhibit bacterial contamination. They have shown positive impacts when used in medical catheters and burn wound dressing. The addition of silver nanoparticles causes a reduction in bacterial growth, preventing the subsequent infection of medical catheters and delayed wound healing in burn victims. Previous work has shown a symbiotic relationship in terms of antibacterial efficacy when nanomaterials and antibiotics have been simply mixed together. A material that effectively combines silver nanomaterials and an antibiotic attached more strongly may show increased performance in medical devices. Here, a novel antibiotic/silver-based nanomaterial hybrid has been synthesized that can be incorporated into medical catheters or wound dressing materials. This material consists of silver nanocubes surrounded by a partial gold shell, allowing for the attachment of a commonly used antibiotic. The toxicity of this material to bacterial strains commonly found in a hospital setting will be examined. Also discussed will be the toxicity of this novel material to environmentally relevant plant species.

Novel antibiotic/silver nanomaterial hybrid as a surface coating on medical devices

250th National Meeting (2015)

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