Membrane has been the subject of great interest in separation process due to its high efficiency and convenience. However, disordered pore structure in membrane process has been a major drawback for separation of target compounds. To overcome this problem, layer-by-layer (LbL) technique is considered as one of most effective methods to control the pore properties of membrane among surface modification techniques. Spray-assisted LbL method is also applied to overcome the conventional dip-coating LbL deposition due to time and material savings. Ultra-thin polyelectrolyte multilayer ultrafiltration (UF) membranes were successfully prepared through spray-assisted LbL technique and characterized by various instruments such as scanning electron microscope (SEM), atomic force microscope (AFM), fourier transform infrared (FTIR) spectroscopy, and zeta-potential analyzer. Efficacy of polyelectrolyte membrane by spray-assisted LbL technique on separation of botulinum toxin and vaccinia virus was investigated. Our fabricated membrane showed greater separation efficiency than bare UF membrane. The results indicate that ultra-thin polyelectrolyte multilayer UF membrane could be an effective material for separation of complex materials in aqueous phase.

Fabrication of ultra-thin polyelectrolyte membrane for separation of botulinum toxin and vaccinia virus

251st National Meeting (2016)

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