2-Amino-oxazole and -thiazole derivatives have been used to treat both Alzheimer’s and other prion-related diseases, and they have also been studied for their anti- inflammatory properties. Chiral oxazole and thiazole derivatives are interesting because of their biological activity and their role as prebiotic genetic precursors. These molecules can be produced under continuous flow conditions in a highly “green” manner using only water as solvent and chiral additives (such as amino acids) to induce biomimetic asymmetry.

Prebiotic flow synthesis of bioactive nucleoside precursors

251st National Meeting (2016)

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