Natural products derived from microbes found in living plant tissues (i.e. endophytes), are a viable and relatively unstudied source of novel compounds with medicinal and agricultural applications. Particularly, natural product research is desirable for the production of antibiotics and agrochemicals which are highly effective, yet may produce less environmental impact and possess lower toxicity than similar compounds produced through synthetic methods. Despite the lower cost of drug production through synthetic methods, large drug companies often pursue natural product research as it can produce unusual model compounds for further modification. From an endophyte cohabitating in a species belonging to the genus <i>Quercus</i>, hydroheptelidic acid was isolated and purified through separation chemistry techniques. The structure of the purified compound was characterized through electrospray ionization mass spectrometry and 2-D NMR spectroscopy techniques including COSY, HSQC, HMBC, and INADEQUATE. Other research indicates that hydroheptelidic acid is bioactive with potential medicinal and agricultural applications

Multidimensional NMR techniques used to elucidate the structure of bioactive hydroheptelidic acid isolated from a <i>Quercus</i> endophyte

251st National Meeting (2016)

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Multidimensional NMR techniques used to elucidate the structure of bioactive hydroheptelidic acid isolated from a Quercus endophyte