Sol-Gels are porous crystalline structures made of silicon oxides. These materials have several applications in industry and optics and may serve as biological or chemical sensors. Sol-gels are ideally employed as sensors due to: (1) no interference of the gel with the encapsulated enzyme’s reactivity, (2) increased protection of sensitive materials, (3) the ability to change the size of pores and (4) the observed high purity of the gel and easy processing at room temperature1. In this undergraduate research project, sol-gels were doped with horseradish peroxidase and glucose oxidase to design a biosensor capable of the detection of glucose via the use of UV-Vis spectroscopy. Kinetics studies were employed to analyze enzymes and compare assays of enzymes. This presentation summarizes the preliminary results and experimental method development. 1Narang, U, et al. Glucose Biosensor Based on a Sol-Gel-Derived Platform. Analytical Chem. 1994, 66, 3139-3144

Design and characterization of a sol-gel glucose biosensor

251st National Meeting (2016)

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