Parabens are esters of <i>p</i>-hydroxybenzoic acid that are commonly used as preservatives in cosmetic products due to their anti-microbial properties. Recent studies have suggested paraben compounds may be toxic to mammalian cells. This poster will explore work toward the synthesis and characterization of novel paraben compounds by the modification of electronic and steric properties of the aromatic ring using both eletrophilic aromatic substitution reactions and modification of diazo derivatives. Preliminary toxicity and photoxicity studies of the paraben derivatives will also be described.

Synthesis and characterization of novel paraben compounds

251st National Meeting (2016)

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