This talk will describe our efforts to assemble and organize polyvalent nanostructured materials.  Polyvalent molecules presenting multiple copies of ligands, have applications ranging from pathogen inhibition to vaccine design. We will describe our recent efforts to design highly active polyvalent molecules.  In particular, we will describe the use of protein engineering methods to control polyvalent display.  We will examine the stimulus-responsive formation of polyvalent assemblies.  We will also discuss recent biological and biomedical applications of polyvalent molecules.

Design and assembly of nanostructured polyvalent materials

251st National Meeting (2016)

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