The "chemical nose/tongue" approach presents a potential alternative to specific biomarker approaches. In this strategy a sensor array is generated to provide differential interaction with analytes via <i>selective</i> receptors, generating a stimulus response pattern that can be statistically analyzed and used for the identification of individual target analytes and also for profiling of complex mixtures. In our research, we have applied this methodoloy to sensing of proteins and cell surfaces, focusing on areas of biomedical importance. This talk will present the use of nanoparticle-fluorophore sensing arrays for diagnostic and high content screening (Figure 1).

Array-based profiling for diagnostics and high-throughput screening

251st National Meeting (2016)

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