Linalool and cinnamaldehyde are essential oils found in lavender and cinnamon bark respectively. Both have been shown to exhibit antimicrobial properties. The antimicrobial properties of chemical derivatives of these compounds have been researched to a lesser extent. Using soxhlet extraction, each compound was extracted from its natural source. The essential oils were purified using chromatography and analyzed using GC/MS, IR and NMR spectroscopy. Derivatives were created using methods such as addition, oxidation, hydrohalogenation and hydroboration-oxidation reactions. The antimicrobial properties of these derivatives were tested against their precursors using the disc diffusion method of antibiotic susceptibility testing. The samples were tested on <i>E. coli</i> and <i>S. aureus</i>. This research looked at the antimicrobial properties of derivatives of each essential oil and establishes a greater understanding of the significance of chemical structure in a compound's ability to function as an antimicrobial agent.

Antimicrobial properties of lavender and cinnamon derivatives

251st National Meeting (2016)

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