The development of precious metal-catalysed reactions has revolutionised the way in which we view synthetic transformations. Pd-catalysed coupling reactions in particular have been widely adopted within the pharmaceutical industry, enabling chemists to quickly and efficiently probe chemical space. With drug candidates growing in molecular complexity, the need for robust catalytic processes is ever present.<br/>In the current economic climate, efficiency and sustainability are key drivers for process chemists and sub-optimal catalytic steps can lead to the use of Pd being designed out of processes. PhosphonicS has developed smart silica technology to enable process chemists to benefit from all the advantages of a Pd-catalysed reaction, whilst still meeting the stringent targets of efficiency, sustainability and regulatory compliance.<br/>PhosphonicS specialises in designing simple solutions to complex purification and precious metal recovery problems from early research all the way through to full scale production.

Smartest silica technology: Getting the most from your Pd-catalysed process

251st National Meeting (2016)

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