ChEBI (http://www.ebi.ac.uk/chebi), a manually curated database and ontology of chemical entities of biological interest, is widely recognized as a key player in the chemical ontology arena. The ChEBI Ontology includes both chemical and functional descriptors of the molecules and groups in the database. This is of particular importance in enabling the incorporation of chemical concepts of importance to chemical biology and drug discovery into resources that have different foci. Thus the ChEBI Ontology is widely used by other biomedical ontologies - most notably the Gene Ontology - for handling their chemistry-containing terms.<br/><br/>After reviewing the motivation behind the development of the ChEBI Ontology and its three component sub-ontologies, the various relationships used to link entities within the ontology and the methods used to classify new entries in the ChEBI database will be described. Finally, plans for future developments of the ChEBI Ontology will be discussed, and possible applications and uses of the ontology by other resources will be outlined.

ChEBI database and ontology: A key resource for chemical biology and metabolomics

251st National Meeting (2016)

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