We report on polypept(o)ides based on hydrophilic poly(sarcosine) and hydrophobic poly((<i>S</i>-thiosulfonyl-l-cysteine), their secondary structure controlled self-assembly into nanoparticles and core cross-linking by disulfide bond formation. The formed disulfide bonds respond to intracellular reduction potentials and hence provide stability in extracellular medium while degrade inside the cell.

Shape-control in self-assembly of bioreducible polypept(o)ides

251st National Meeting (2016)

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