We analyzed the kinetics of three variants of the carbapenem-hydrolyzing class D β-lactamases OXA-24/40 including the wild type (WT) variant, a G222A variant, and a G222V variant. The emergence of OXA-24/40 and other class D β-lactamases has resulted in an increase in β-lactam antibiotic resistance in the <i>Acinetobacter</i> genus. Hence this research is relevant in a medical setting.

Kinetic analysis of OXA-24/40 variants against aztreonam & cephalothin

251st National Meeting (2016)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.