Parabens are anti-microbial preservatives found in cosmetics, toiletries, and pharmaceuticals. Methyl paraben, butylparaben, and isopropylparaben are used in order to preserve products applied to the skin. It has been shown that these compounds may be toxic to mammalian cells by acting as hormone agonists or antagonists or cellular enzyme inhibitors, or due to analgesic or anesthetic effects. This poster will describe a collaborative undergraduate project within our department to synthesize and characterize chlorinated paraben derivatives as well as to study the toxicity and phototoxicity of these compounds.

Synthesis, characterization, and toxicity studies of chlorinated paraben derivatives

251st National Meeting (2016)

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