The Hypericum genus, consisting of over 450 species, is a rich source of structurally diverse natural products. Previous phytochemical studies of several members of the genus have afforded flavonoids, xanthones and acylphloroglucinol derivatives as the major classes of secondary metabolites. There has been much interest in these classes of compounds because of their anticancer, antioxidant, antimicrobial and anti-inflammatory properties. In the current study, an hexane extract of the leaves of H. densiflorum was purified by a combination of silica gel column chromatography and reversed phase HPLC to afford O-prenylated acylphloroglucinol derivatives and triterpenes. The structures of the purified compounds were elucidated by 1D and 2D NMR spectroscopic data.

Chemistry of an hexane extract of Hypericum densiflorum

251st National Meeting (2016)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.