Modern organic chemistry is hard to imagine without diazo compounds, such as CH2N2 (diazomethane) and N2CHCO2Et (ethyl diazoacetate). In 2014 we have developed two novel chemical reagents - CF2HCHN2 (1)1 and C2F5CHN2 (2).2-4 Along with the known CF3CHN2 (3),5-7 these reagents can be used in various synthetic transformations: cyclopropanation, carbene insertion, [3+2]-cycloaddition, Japp-Klingemann reaction, etc. We believe that novel reagents 1, 2 and 3 will find soon wide applications in pharmaceutical industry and agrochemistry. 1. P. K. Mykhailiuk Angew. Chem. Int. Ed. 2015, 54, 6558. 2. P. K. Mykhailiuk Beilstein J. Org. Chem. 2015, 11, 16. 3. P. K. Mykhailiuk Org. Biomol. Chem. 2015, 13, 3438. 4. P. K. Mykhailiuk Chem. Eur. J. 2014, 17, 4942. 5. E. Y. Slobodyanyuk et al. Eur. J. Org. Chem. 2014, 2487. 6. E. Y. Slobodyanyuk et al. Eur. J. Org. Chem. 2014, 3592. 7. O. S. Artamonov et al. Synthesis 2013, 225.

Novel fluorinating reagents - fluorinated diazoalkanes

251st National Meeting (2016)

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