This paper will discuss recent advance in applying RAFT single unit monomer insertion (SUMI) as an approach to sequence controlled polymers. Recently, we published1 on the automated parallel synthesis of higher order quasi-multiblock (BAB, CBABC, ABC and ABCD) copolymers using the ChemspeedTM platform to illustrate the utility of a high-throughput approach for the one pot synthesis of functional polymers of increased complexity. The process is summarized in the Figure. With methacrylate monomers a lower limit on the length of block inserted is imposed by the low transfer constant of the RAFT agent, which means that single unit monomer insertion (SUMI)2 is not possible. In this paper, we describe application of a similar strategy to other monomers with a view to defining the advantages and limitaions inherent in each system.

RAFT single unit monomer insertion (SUMI) and monomer sequence control

252nd National Meeting (2016)

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