Ru(II)Pt(II) bimetallic complexes consisting of a ruthenium based chromophore coupled to a cisplatin moiety have been shown to display multifunctional interactions with DNA. Herein, we will discuss the impact of position of the methyl group on bipyridine ligand on photophysical and redox properties of Ru(II)Pt(II) bimetallic complexes. Two Ru(II)Pt(II) based metal complexes, [Ru(4-Mebpy)2dppPtCl2](PF6)2 and [Ru(6-Mebpy)2dppPtCl2](PF6)2, were synthesized and characterized (dpp =2 3-bis(2-pyridyl)pyrazine and 4-Mebpy = 4'-methyl-2,2' bipyridine, 6-Mebpy = 6'-methyl-2,2' bipyridine). Photochemical, electrochemical, and DNA interaction properties of designed metal complexes will be discussed.

Substituent effects on the photochemistry and DNA interaction properties of Ru(II)Pt(II) based polypyridyl complexes

252nd National Meeting (2016)

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