Design and synthesis of new serie 6-(het)arylimidazo[2,1-b]thiazole derivatives possessing pyridine moiety are described.Their<i> in vitro</i> cytotoxity activities against of one human non-small cell lung cancer were tested. Its IC<sub>50</sub> value over A549 cells and EGFR kinase were 0.611 µmol and 112.4 nM, respectively.

Structure-based, in molecular design and synthesis of inhibitors of protein kinase family of receptors of epidermal growth factor

253rd National Meeting (2017)

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