Viruses that infect bacteria (i.e., bacteriophages) are the most abundant biological entities on earth and the selective pressures imposed by these pervasive predators have a profound impact on the composition and the behavior of microbial communities in every ecological setting. Our work aims to understand the mechanisms that bacteria use to defend themselves from viral infection and the counter measures that viruses use to subvert bacterial immune systems. Conflict between viruses and their hosts promotes biological innovation and our work aims to determine molecular structures of cellular machines that are responsible for waging these biological battles.

CRISPR immune response to viruses that infect bacteria

253rd National Meeting (2017)

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