Nanoparticles are of importance in biomedical applications due to their intrinsic properties. The ligand coating of the nanoparticles is critical for colloidal robustness and nanoparticle function and the chemical composition/morphology of the inorganic core is important in defining/tuning the optical, electrical and magnetic properties of the nanoparticulate system. As the chemical synthesis of nanoparticles and nanoparticle functionalization techniques advance during the years, the design of nanoparticulate systems become more sophisticated facilitating multitasking nanoparticle roles.<br/>In this presentation I will discuss recent progress in our group concerning the design of nanoparticles and their incorporation in biological systems to facilitate sensing, drug delivery and accurate manipulation. My talk will focus on a new class of nanoparticles that can accommodate synergistic actions of sensing and drug delivery in cells. These multitasking particles are able to selectively release their therapeutic payload in response to specific mRNA signatures and selectively kill model cancerous cells as opposed to healthy cells.

Targeted sensing and drug delivery using smart nanoparticles

253rd National Meeting (2017)

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