The Methamphetamine Profiling Program conducts in-depth chemical analysis of illicit methamphetamine samples to establish trends associated with the manufacture of methamphetamine. Organic impurity profiling of methamphetamine provides valuable information, including synthesis method and precursors. One of the most common methamphetamine synthesis routes uses 1-phenyl-2-propanone (P2P) and methylamine. Recent impurity profiles indicate that nitrostyrene has been used to clandestinely produce P2P. In this study, methylamine is synthesized from formaldehyde and used to produce methamphetamine using P2P made from the nitrostyrene method. The impurity profile of this methamphetamine will be compared to that of illicit methamphetamine samples that were produced from the nitrostyrene method.

Impurity profiling of methamphetamine synthesized from clandestine methylamine

253rd National Meeting (2017)

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