Cellulose is a natural, harmless and biocompatible polymer, so it is considered a model material with a lot of uses. In addition it can be extracted from different sources, which include algae; the algae cellulose has the advantages of not having lignocellulosic complex in their cell wall and this facilitates its extraction and at the same time allows a particular structural characteristics [1]. On the other hand, gold nanoparticles (NPAu) are inert materials with an infinite number of therapeutic applications from antibiotic up to anticancer and have been widely studied. Finally bovine serumn albumin (BSA) is a globular protein considered as a multifunctional carrier, i.e., serves as transporter protein model to protect and improve nanoparticles access to the active sites. In this work, with the intention to understand the mechanisms of interaction and surface adsorption of these materials and thus evaluate the potential applications that they may have together, we will present results on the formation of thin film cellulose coated surfaces as well as different functionalization strategies with chitosan and alginate, and compare their advantages as supports for immobilization of NPAu-BSA complexes. For this purpose, viscoelastic properties of cellulose or cellulose-chitosan/alginate surfaces are measured by frequency and dissipation shifts in a Quartz Crystal Microbalance at different physicochemical conditions, followed by adsorption of the hybrid nanomaterial. In addition, preliminary results of the interaction and viscoelestic properties of cellulose-chitosan-NPAu-BSA films at the air-water interface using an Interfacial Shear Rheometer, will be presented.

Adsorption and viscoelastic studies of gold Nanoparticles (NPAu) and Bovine Serum Albumin (BSA) complexes at chitosan-alginate-cellulose films

253rd National Meeting (2017)

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