Amphiphilic diblock copolymers can assembled into multiple nanoscale morphologies. These morphologies are predictable as functions of the volume fraction of its block components and they can vary from spheres, cylinders and lamellar structures. In this work, we have investigated the distribution of nanodiamonds (ND) (with an average diameter of ~ 6 ± 4 nm) into well-ordered templates afforded by poly(styrene-block-ethylene oxide) (PS–PEO) solutions, in both N, N-dimethylformamide (DMF)/water and Toluene. The outstanding and unique properties of nanodiamonds could support the development of novel bionanomaterials that perform a controlled placement of bioactive nanoparticles, which shows to promote better cell adhesion. Human fetal osteoblastic cells (hFOB) were seeded on PS-PEO self-assembled surfaces during 1 and 7 days of cell culture to investigate adhesion, proliferation and morphology by immunocytochemistry assays. Surface morphology and cell attachment were observed by Scanning Electron Microscopy (SEM) and micro-phase domains were observed by Atomic Force Microscopy (AFM). This results demonstrate the potential of incorporation bioactive functionalities to block copolymers by the incorporation of nanodiamonds.

Development of engineered bionanomaterial based on dispersed nanodiamonds into self-assembled polystyrene-block-poly(ethylene oxide) copolymer

253rd National Meeting (2017)

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