Although nanocrystals are used already in may applications, the knowledge on their formation is still in its infancy. We will present results on nucleation and growth of quantum dots obtained from uv-vis spectroscopy and x-ray scattering data obtained in a rapid continuous flow apparatus. A second part of the talk deals with the formation of iron oxide nanocrystals by thermal decomposition of iron oleate. We have identified a set of clusters being formed before particle formation starts. We will discuss parameters determining the final size and shape of the nanocrystals.<br/>The key idea for using nanocrystals for biomedical diagnostics is to benefit from their outstanding physical properties in the visualization of biological events or malignant cells or tissues. This requires a special design of the ligand shell, which preserves the fluorescent, magnetic and plasmonic properties of the particles in the biological environment on one side and allows a specific targeting on the other. The lecture reports on different chemical approaches and describes factors determining the biological response on fully synthetic nanocrystals. We will highlight concepts based on PEGylation and show how small deviations in the ligand shell alters the behavior in biological environment substantially.

Observation of nucleation and growth during the formation of cadmium selenide and iron oxide nanoparticles and their use for biomedical imaging

253rd National Meeting (2017)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.