We have developed selective oxidative palladium-catalyzed borylative and arylative carbocyclizations of enallenes, allenynes, and bisallenes as well as C-H activation/carbocyclization of arylallenes. These reactions have been used in a number of useful cascade reactions. Many of these cascade reactions employ molecular oxygen as the oxidant in a biomimetic approach.<br/><br/>In another approach to biomimetic catalysis, enzymes have been combined with racemization catalysts for dynamic kinetic resolution. An example of the latter approach is the development of a biomimetic hybrid catalyst that works as an artificial metalloenzyme.

Biomimetic catalysis in green organic transformations

253rd National Meeting (2017)

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