Bisphenol A (BPA) is an endocrine disrupting chemical (EDC) of emerging concern, because of its capability to mimic hormone functions in human and aquatic life. BPA is commonly used in plastic and food packaging industries. A number of studies have reported that BPA is able to enter into the human body through ingestion or skin contact. Once in it, can cause various health issues such as obesity, cancer, developmental problems, and infertility, among other things. BPA has been found in different food sources, such as milk, which is the major foundation for infant diet. To ensure infant’s welfare, it is important to monitor BPA and other EDCs levels in milk. There are many existing methods for the detection of BPA in milk. Since BPA has high affinity to lipids in milk its extraction is hindered, and therefore, many of these methods require a great amount of time and or use of organic solvents. The aim of this project was to develop a simple, solventless, and sensitive method capable of analyzing BPA levels in milk. A “green” sample preparation technique called stir-bar sorptive extraction (SBSE) coupled with Thermal Desorption/Gas Chromatography/Mass Spectrometry, was used. Extraction efficiency of BPA from milk was studied by looking into different variables, such as pH, temperature, sonication time, EDTA addition, and sample size. Optimized method will be applied to the analysis of BPA in breast milk to assess neonatal exposure to BPA.

Method development for the analysis of Bisphenol A (BPA) in milk

253rd National Meeting (2017)

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