Molybdenum(IV)oxophthalocyanines were synthesized from substituted (-F, -NO2, -CH3) 1,2-dicyanobenzenes with ammoniumheptamolybdate-tetrahydrate in melt at 170°C. Purification via sublimation at 450°C and 0.06 mbar was successful for the unsubstituted material and gave a dark blue powder. The compounds were characterized with IR, UV/VIS and powder diffraction. The Mo=O vibration in IR spectra of the unsubstituted Molybdenum(IV)oxophthalocyanine (965 cm-1) and the calculated vibration at 994 cm-1 shows good agreement and indicates the desired oxidation state of +IV for molybdenum - the absence of the Mo≡N vibration at 1078 cm-1 confirms this. As Molybdenum(IV)oxophthalocyanines are thermally and chemically very stable, they are well-suited to study the influence of substituents on Szilárd-Chalmers-reactions: Bombardment of a nucleus (98Mo) in a chemical compound with thermal neutrons can lead to the breaking of the chemical bonds and, therefore, ejection of the activated nucleus (99Mo) from the target material. 99Mo is especially interesting for medical applications since neutron capture by 98Mo (natural abundance: 24.4 %) yields 99Mo, which in turn by decay, yields medically important 99mTc. The highest activities were obtained with the unsubstituted Molybdenum(IV)oxophthalocyanine, whereas the highest yields of carrier-free 99Mo after separation were obtained with the NO2 and CH3 substituted phthalocyanines (&gt;90 %).

Molybdenum(IV)oxophthalocyanines for Szilárd-Chalmers production of 99Mo

253rd National Meeting (2017)

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