Describing the interaction of organic cations and zwitterions with dissolved natural organic matter requires the pH-dependent speciation of both the sorbate and the sorbent to be considered, as well as the influence of competing inorganic cations. We have studied the pH-, ionic strength-, and concentration-dependent binding to dissolved soil organic matter of several pharmaceutical compounds that bear cationic moieties at pH values typical of environmental systems. We have employed equilibrium dialysis experiments, saturation-transfer difference NMR spectroscopy, and the nonideal competitive adsorption (NICA)-Donnan model to gain insight into the interaction between organic cations and zwitterions with dissolved organic matter. We will discuss recent results from experiments including competition with inorganic cations.

Interaction of cationic pharmaceuticals with dissolved natural organic matter

253rd National Meeting (2017)

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