Flow Chemistry is commonly seen as a cutting-edge chemical and process intensification approach. It is the most advanced concept in the emerging continuous production on small-scale. In May 2015 the FDA called on pharma manufacturers and CMOs to begin to switch from batch to flow up the year 2025. Flow chemistry provides chemical intensification and opens Novel Process Windows through exploration of unusual and typically harsh process conditions with, a.o., much enhanced activation. Herein, photo¬catalytic micro-flow synthesis is on the edge of giving a large push to synthetic chemistry. Yet, the big chance is to make the chemistry entirely different, e.g. by (a) reactor flow cascades which shrink multi-step syntheses together; (b) direct green pathways from inactive, non-functionalized resource materials (C-H activation, N fixation, CO<sub>2</sub> utilization).

Flow chemistry: An enabler for space chemistry

253rd National Meeting (2017)

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