Organosilanes are important intermediate functional groups that are used in a wide range of different transformations.  However, the reaction conditions required to synthesize an organosilane are usually rather harsh, which limits functional group compatibility, or requires the use of specialized reagents that are difficult to synthesize and work with.  Disilanes, which are air-stable and readily available, can be used as an alternative silylating reagent.  Additionally, the use of copper as the catalyst would produce a copper silyl complex that can provide enhanced functional group tolerance over many current silylation strategies.  Efforts towards developing copper(I)-catalyzed silylations with disilanes as the silicon source will be presented.

Copper(I)-catalyzed silylations using disilanes

253rd National Meeting (2017)

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