Fluorescent nanodiamonds (FNDs) are emerging as advanced quantum materials for biomedical applications and precision sensing due to their unique optical and magnetic properties. FNDs are obtained by implementing elemental defects into the threedimensional carbon lattice, such as the nitrogen vacancy (N-V), giving unconditionally stable fluorescence without bleaching or blinking even after several months of continuous excitation. The emission wavelength of FNDs is not size-dependent and is tuneable from the visible to the near infrared region according to the elemental lattice defects. Moreover, the N-V center in FNDs serves as single-spin sensor that locally detects even tiniest magnetic fields offering great potential for atomic resolution imaging under physiological conditions.<br/>The preparation of high quality N-V nanodiamonds, the chemistry of surface modification with i.e. biopolymers and proteins as well as the precise assembly of FNDs on DNA origami or FND-nanogold hybrid particles will be discussed. The advent of diamond quantum materials promises solving the longstanding goal of single molecule detection with atomic resolution under ambient conditions and opens great opportunities for various biomedical applications such as enhanced magnetic resonance imaging (MRI).<br/><br/>

Fluorescent nanodiamonds for precision sensing & drug delivery applications

253rd National Meeting (2017)

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