In recent years, the developement of strategies aiming at using DNA to guide the assembly of nanoparticles has been the focus of intense research, with potential applications in medical diagnostics, catalysis and plasmonics. In line with these experimental advances, the parameterization of coarse-grained models for such systems has also made great strides in recent years, allowing to shed light on the dynamics and assembly of DNA grafted nanoparticles. In this work, using coarse-grained models, we carry out nonequilibrium molecular dynamics simulations to elucidate the rheological behavior of DNA grafted gold nanoparticles and elucidate the role of the length of the DNA chains attached to the gold nanoparticles, of their number and of the role the sequence complementarity on their transport properties.

Molecular simulation of transport of DNA grafted nanoparticles

253rd National Meeting (2017)

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