Natural Products (NPs) are key to medicine, yet the generation of analogues of these important compounds can often be challenging. In this talk, I will report success in compound modification using an exciting new approach to NP analogues pioneered by the Goss lab. By developing new, mild, aqueous and selective cross-coupling chemistries the selective diversification of organic molecules, and in particular NPs, containing carbon-halogen bonds has been successfully achieved.

Selective functionalisation and diversification of halogenated compounds through mild aqueous cross-coupling methodologies: From organic molecules to natural products

253rd National Meeting (2017)

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