In this presentation, a multiplexed molecular detection platform based on the fluorescent emissions of single wall carbon nanotubes will be presented. The carbon nanotubes are non-covalently modified with chelating group nitrilotriacetic acid and Cu 2+ ions. By conjugating a recognition moiety with the Cu2+ ion, the carbon nanotubes are capable of specifically recognize the target analyte transduced by their changed fluorescence emission properties. Moreover, we have developed a miniature mircorarray system to integrate multiple recognition sites onto a small area of glassslide. Using only a few microliter of the sample, we are able to quickly detect multiple analytes using our nanosensor platform. The label-free system will be of great potential for product quality control and clinical diagnosing applications in the future.

Label-free optical biomolecular sensing using single wall carbon nanotubes

254th National Meeting (2017)

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