A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptionally good insecticidal activity controlling a number of insect species.  In this presentation, we will report the discovery, optimization, and Structure-Activity Relationship (SAR) study which led to the discovery of triflumezopyrim, a potent hopper insecticide.

Triflumezopyrim (DuPont Pyraxalt®): Discovery and optimization of mesoionic pyrido[1,2a]pyrimidinones as a novel class of insecticides

254th National Meeting (2017)

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