IVCC is a Product Development Partnership (PDP) investing donor funds in R&D to overcome barriers to innovation in vector control. Vector control, through LLINs and the use of IRS has been instrumental in cutting global malaria mortality rates by half since 2000. Current insecticides are compromised by insecticide resistance, the impact of which is reaching a tipping point. Lack of market incentive for independent commercial development, coupled with the risks associated with public health product development, means that the role of the wider public health community in sustaining the development process is essential.<br/> <br/>Since 2008, research-based agrochemical companies have provided access to their chemical libraries, with 4.5 million chemical compounds reviewed for activity against public health vectors. After a evaluating 27 classes of chemistry and several major synthesis programs,  nine compounds from five chemical classes have been identified as having potential for vector control use. Within the next year, three compounds will be promoted to full development, providing a suite of new chemical tools to support the malaria elimination and eradication agenda.  Multiple classes of insecticide with different modes of action will facilitate vector control IRM in line with the WHO Global Plan for Insecticide Resistance Management (GPIRM), reducing the risk of insecticide resistance developing in the future.  Success in protecting people with IRS and LLINs means that the focus of future development will also be on eliminating outdoor transmission of insect-borne disease. Using the Expert Scientific Advisory Committee (ESAC) model, in partnership with industry know-how, has been highly effective for the discovery and development of novel vector control solutions.<br/>

Bringing new products to market: Collaborative efforts leading to innovative solutions in vector control

254th National Meeting (2017)

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