The N-(5-Aryl-1,3,4-thiadiazol-2-yl)amides are a new class of insecticides with activity against a variety of sap feeding pests. An N-alkyl-3-(alkylthio)propanamide and a 3-pyridinyl ring had been found to be excellent substituents at the 2- and 5-positions of the 1,3,4-thiadiazole ring, respectively. In an attempt to increase biological activity and broaden sap-feeding pest spectrum, an investigation of the nitrogen and sulfur substituents of the N-(5-aryl-1,3,4-thiadiazol-2-yl)amides was performed. The synthesis and biological activity of relevant molecules will be discussed.

Investigation of heteroatom substituents in insecticidal N-(5-aryl-1,3,4-thiadiazol-2-yl)amides

254th National Meeting (2017)

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