Vapour phase spatial repellents deter mosquitoes from attacking humans in a protected space. More recently, developed mathematical models suggest that highly efficacious spatial repellents are likely to be effective when used outdoor in areas where transmission commonly occurs outside. The aim of this study was to assess personal protection in terms of the proportion of reduction in mosquitoes attacking human volunteers by comparing the number of <i>An. minimus</i> mosquitoes landing upon volunteers wearing transfluthrin (TFT)-treated[1] or untreated clothing in a semi-field condition. Unfed female mosquitoes were collected from a double-net holding cow bait tethered inside the inner net and were released in a screened semi-field room (n=100 mosquitoes) the following morning. Number of mosquitoes landed on untreated volunteer was significantly lower from treated one (P&lt;0.05). In addition, double-blinded, Latin-square design that utilized human-landing catches from treated or untreated volunteers in order to measure repellency was conducted. A piece of TFT PET sheet was stitched to the back of the vest. During the human-landing catches, the volunteers wore shorts to the knee, work boots, and a lone-sleeve vest to ensure that blood-seeking mosquitoes had access only to their lower legs. Results revealed that TFT-treated provides 50-70% significant bite protection as compared to the control in both semi field and outdoor setting. We conclude that bite protection of transfluthrin-treated vests could potentially be used against malaria vectors in an outdoor field setting.<br/>

Field evaluation of tranfluthrin against outdoor biting mosquito in Thailand

254th National Meeting (2017)

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