A series of enantiomerically pure aryl alkyl sufones was synthesized from <i>L</i>-serine, and subjected to fluorination. Effect of base and aryl moiety on diastereoselectivity of fluorination will be presented, as also the epimerization at the fluorine-bearing stereogenic center.

Stereodiverse synthesis of chiral aryl fluoroalkyl sulfones, from a single chiral precursor

254th National Meeting (2017)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.