Traditional molecularly imprinted polymers are bulk, macroporous polymers with poor solubility. Water-soluble MINPs were prepared by cross-linking of surfactant micelles in the presence of templates. Fluorescence sensor can be installed after cleaving the template. The rest space in the created pocket would be complementary to the guests. With fluorescence groups in the binding pockets, the MINPs could detect small organic molecules including drugs directly by fluorescence.

Water-soluble molecularly imprinted nanoparticles (MINPs) as turn-on fluorescence sensors

254th National Meeting (2017)

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