Rapidly growing public repositories at NCBI provide extensive resources for biomedical discovery: including biomedical literature records, genomic and chemical data. In this situation, uncovering interrelations between different pieces of data and representing available knowledge in an easy-to-comprehend form becomes a major challenge. The amount and diversity of data linked to the records varies drastically, with information being abundant in some cases and very limited or completely unavailable in others. While it is important to provide any available piece of information for compounds with very limited information available, well-studied compounds may have links to thousands of documents and co-occur with many disease, gene and protein terms there. It is desirable to represent available information in a compact aggregated default form on a PubChem summary page, potentially allowing refinements. This talk will detail current efforts towards improving chemical-disease and chemical-gene/protein linking in PubChem.

Towards linking chemical-disease and chemical-gene/protein information in PubChem

254th National Meeting (2017)

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