Batrachochytrium dendrobatidis (Bd) is a fungal pathogen that causes chytridiomycosis, a lethal amphibian skin infection linked to worldwide population declines. The cutaneous bacterial species Janthinobacter lividum provides one level of protection against Bd by producing the antifungal metabolite violacein. Our hypothesis is that Bd and its bacterial antagonists chemically interact. To test this, J. lividum was cultured in the presence of methylthioadenosine (MTA) and kynurenine, which are compounds produced by Bd. High performance liquid chromatography was then used to monitor violacein production, and standard cell counting assays were used to determine bacterial growth.

Microbial chemical ecology: Molecular interactions between Batrachochytrium dendrobatidis and Janthinobacter lividum

254th National Meeting (2017)

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