Among other plasmonic nanoparticles, surfactant-free branched gold nanoparticles have shown extraordinary performance as a photothermal transducer for cancer treatments and a platform for surface enhanced Raman spectroscopy-based bio/chemical sensing and imaging applications. The effectiveness and reliability of branched gold nanoparticles in biomedical applications rely strongly on the consistency and reproducibility of physical, chemical, optical and therapeutic properties of nanoparticles. Herein, we present the optimization of the bottom-up synthesis that improves reproducibility and homogeneity of plasmonic branched-nanoparticles, and the modulation of the morphology, particularly the branch density, dimensions and sharpness of branches to obtain desired optical properties and loading capacities of therapeutic agents on nanoparticles.

Modulation of morphology and optical properties of surfactant-free plasmonic branched nanoparticles

254th National Meeting (2017)

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