Laboratories analyzing semi-volatile organics by methods such as Method 625 and Method 8270 typically use 0.25 mm ID capillary columns.  Depending on method conditions, simply running the required quality control (QC) samples can consume a significant portion of 12 –hour shift, leaving less time for analysis of revenue generating samples.  A cycle time for a single injection on a standard single quadrupole Gas Chromatograph Mass Spectrometer (GCMS) may be as long as 30 minutes.   You may only have time for 18 actual samples before having to verify the tune.<br/> <br/>This poster describes development of a GCMS method using narrow-bore (0.15 mm ID) columns, rapid oven heating and cooling, and rapid data acquisition to decrease the runtime while maintaining the strict QC requirements of EPA methods. A sensitive fast-scanning quadrupole mass spectrometer is necessary for identification and quantitation of target compounds at sub-nanogram levels.<br/> <br/>This poster presents instrument operating conditions, and method performance statistics including linearity, accuracy, precision, and detection limits for all compounds.

76% increase in throughput for determination of semi-volatiles using narrow-bore GC columns and rapid data acquisition with a highly sensitive quadrupole GCMS system

254th National Meeting (2017)

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